zaterdag 11 oktober 2025

The origin of Eastern European Jews revealed by autosomal, sex chromosomal and mtDNA polymorphisms

 Biol Direct

. 2010 Oct 6:5:57.
 doi: 10.1186/1745-6150-5-57.

The origin of Eastern European Jews revealed by autosomal, sex chromosomal and mtDNA polymorphisms

Avshalom Zoossmann-Diskin 1
Affiliations 

Abstract

Background: This study aims to establish the likely origin of EEJ (Eastern European Jews) by genetic distance analysis of autosomal markers and haplogroups on the X and Y chromosomes and mtDNA.

Results: According to the autosomal polymorphisms the investigated Jewish populations do not share a common origin, and EEJ are closer to Italians in particular and to Europeans in general than to the other Jewish populations. The similarity of EEJ to Italians and Europeans is also supported by the X chromosomal haplogroups. In contrast according to the Y-chromosomal haplogroups EEJ are closest to the non-Jewish populations of the Eastern Mediterranean. MtDNA shows a mixed pattern, but overall EEJ are more distant from most populations and hold a marginal rather than a central position. The autosomal genetic distance matrix has a very high correlation (0.789) with geography, whereas the X-chromosomal, Y-chromosomal and mtDNA matrices have a lower correlation (0.540, 0.395 and 0.641 respectively).

Conclusions: The close genetic resemblance to Italians accords with the historical presumption that Ashkenazi Jews started their migrations across Europe in Italy and with historical evidence that conversion to Judaism was common in ancient Rome. The reasons for the discrepancy between the biparental markers and the uniparental markers are discussed.

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References

    1. Zoossmann-Diskin A, Joel A, Liron M, Kerem B, Shohat M, Peleg L. Protein electrophoretic markers in Israel: compilation of data and genetic affinities. Ann Hum Biol. 2002;29:142–175. doi: 10.1080/03014460110058971. - DOI - PubMed
    1. Bonné-Tamir B, Zoossmann-Diskin A, Teicher A, Oppenheim A, Nevo S. In: Isolation migration and health. Roberts DF, Fujiki N, Torizuka K, editor. Cambridge: Cambridge University Press; 1992. Genetic distance analyses in Israeli groups using classical markers and DNA polymorphisms in the β-globin gene; pp. 87–106.
    1. Zoossmann-Diskin A, Gazit E, Peleg L, Shohat M, Turner D. Thrombophilic polymorphisms in Israel. Blood Cells Mol Dis. 2008;41:230–233. doi: 10.1016/j.bcmd.2008.05.004. - DOI - PubMed
    1. Ankory Z. In: Genetic diseases among Ashkenazi Jews. Goodman RM, Motulsky AG, editor. New York: Raven Press; 1979. Origins and history of Ashkenazi Jewry (8th to 18th century) pp. 19–46.
    1. Hendelssmann Y. In: The History of the people of Israel. Shavit S, Shamir I, editor. Givataim, Israel: Massada; 1985. The Jewish centre in Ashkenaz in the 10-13th centuries; pp. 72–73. (in Hebrew)

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